Author Vanessa Bertolucci

Research · Methods · Scientific Writing

Translational Biochemistry Issue 2026 vanessabertolucci.com

Methods & reporting

Scientific Governance

Clear reporting is not decoration. It is part of the scientific method.

Editorial position

Guidelines protect interpretation.

Reporting guidelines help authors show what was planned, done, measured, analyzed, and concluded. They reduce ambiguity and make peer review more precise.

The correct guideline depends on the study design. A trial, a systematic review, an observational study, a diagnostic study, and an animal experiment do not require the same reporting structure.

Guideline index

Core frameworks

Study typeGuidelineUse
Randomized trialsCONSORT · SPIRITIntervention trials and protocols.
Observational studiesSTROBECohort, case-control, and cross-sectional studies.
Systematic reviewsPRISMAEvidence synthesis and meta-analysis.
Diagnostic accuracySTARDDiagnostic accuracy studies.
Prediction modelsTRIPOD+AIModels, prognostic tools, and AI reporting.
Animal studiesARRIVEPreclinical and in vivo experiments.
Economic evaluationCHEERSHealth economic analyses.

Before writing

Plan with the checklist

Use guideline items before drafting, not only before submission.

During writing

Map the evidence

Place each required item where the reader can actually find it.

Peer review

Review with structure

Use reporting items to make comments precise, fair, and actionable.